This issue has been raised and requested for discussion in another thread as well, so I'm going to get it started as well and open for discussion.
There is now Biggysmallz
For Nanocost we have recently received new Items, Ofab Agent Sleeves and Special Edition Helmet, as well as research, Intuition 9 granting us a potential extra -17% Nanocost, -19% with Made perks as well, which does go a long way to helping, I think however that more -%nanocost would be nice.
As for Nano Init. we have recently received Agent's Ring of Aim which is a big help to those who would be short otherwise, whterh we need more or not, I don't know, I believe after 1200 nano init, the reduction in time to cast nano's only decreases 1 second for every 600 points of nano init, 200 points per second reduction before 1200, with my Nano init at 1336 without the ring, I'd need another 400 to 500 points of Nano Init. to make a difference, whether this is the same for others though I don't know, nor do I know how much the Agg/Def Slider effects things, I can virtually instantly cast CH at full def though.
Finally some Nano Delta would be nice to have, lots would be very nice, as far as I can tell we don't have any items that add to it for our profession, nor do any of our symbiants add to it, and yet we have nano formulas that require huge amounts of Nano to cast.